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In most jurisdictions, the endowment agreement is a legal document and as
such the conditions need to be adhered to by both parties.
If a donor is deceased then since the original donor is the one that agreed, you would need to go to court and demonstrate why the changes in the agreement need to take place. The court would make a decision based on the supporting documentation and other evidence.
If appropriate, it may be worthwhile to contact remaining family members to obtain their approval.